The disfigured faces of people hospitalised with maxillofacial cancer do not send out the signals of recognition classically expected in an interaction. Somewhere between human and inhuman, between familiar form and shapelessness, the disfigured face is a terrifying image that no longer has the contours of the original flesh. In such situations, the clinician is often directly confronted with “the other side of the flesh of the face” (Lacan, 1991a). In considering these deformed faces, which can conjure up the figure of the monster in the viewer’s perception, we will try to make the link with the mythical figure of Medusa. How can the clinician avoid the risk of emotional collapse, confronted with these visages médusants? How can they prevent the “head of Medusa” horrifying them? How can we move beyond this moment of shock, so that we can make this clinical encounter possible and conduct a session that will prove therapeutic for these subjects? Based on the myth of Perseus, we will try to draw a parallel with the figure of the analytically-oriented clinician. In this way, we will form some hypotheses on a new circulation of the fantastical chain and the emergence of possibilities for encounters with these subjects.